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- What is CBD?
Discovered in 1940, CBD or Cannabidiol is one of the 113 identified cannabinoids found in the cannabis plant. CBD accounts for up to 40% of the plant’s extract. In recent years, clinical research on the impact of CBD has accelerated. Health and wellness issues related to cognition, pain management, and movement are showing clinical improvement by cannabis extracts containing high amounts of CBD.
- What are Cannabinoids?
Cannabinoids are chemicals that are known to influence human cannabinoid receptors. They can also be distinguished by specific chemical makeup, as they have a particular chemical foundation.
There are 3 main types of cannabinoids, endogenous, phyto, and synthetic. The human body produces its own endogenous cannabinoids, the cannabis plant provides phytocannabinoids, and synthetic cannabinoids are manufactured in a laboratory.
The two main cannabinoids that are used today are THC (tetrahydrocannabinol) and cannabidiol (CBD). THC carries medicinal benefits but is psychoactive and illegal to sell over the counter in the USA. CBD has many medical benefits but doesn’t affect cognition negatively, CBD is not a controlled substance.
- How does CBD work?
Cannabidiol (CBD) has various physiological effects. CBD interacts with inflammatory enzymes, fatty acid enzymes, vanilloid receptors, and more. The COX inflammatory system is the target of NSAID drugs like ibuprofin, CBD molecules are able to inhibit the COX enzymes in a similar way as common NSAIDs.
The endocannabinoid system (ECS) was discovered in the early 1990s. It is the body’s network of cannabinoid receptors and endogenous cannabinoids that regulate core physiological functions. CBD has an effect on the endocannabinoid system similar to that of a reuptake inhibitor. The body’s primary endocannabinoid is called anandamide, a fatty acid neurotransmitter that is broken down by fatty acid enzymes. CBD blocks the primary fatty acid enzyme called fatty acid amide hydrolase (FAAH), thus increasing the amount of CBD present in the brain and body.
- What’s the difference between CBD and THC
THC and CBD are both phytocannabinoids produced by the cannabis plant. They are similar in structure but distinct in character. Selective breeding has proven effective at increasing the concentration of either cannabinoid in the cannabis plant. For example, the high THC strain OG Kush has upwards of 30% THC in it and less than 5% CBD whereas the high CBD strain ACDC has upwards of 30% CBD in it and less than 5% THC.
We are now able to isolate many cannabinoids including THC and CBD. The pharmacology of these isolated compounds are very different. THC has a mental effect that overshadows it’s therapeutic values, even though there are medical benefits of THC. CBD on the other hand is actually a mental stabilizer, and the medical benefits outweigh any psychological effects, which are minor if any.
- What are terpenes?
Terpenes, or “Terps,” are molecular building blocks. They are naturally present in plant oils as well as produced metabolically by animals. Terps are stacked and modified to create the vast array of more than 55,000 different terpenes that have been discovered thus far. In animals, the terpene squalene is used as a precursor for steroid hormones. Many terpenes are highly therapeutic, while others are inert, and some are even harmful.
There are more than 200 identified terpenes in the cannabis plant alone, they have been selectively bred into the plant to provide specific effects. It is the combination of the terpene profile and the cannabinoid profile that gives a particular weed strain it’s unique characteristics.
Chemical elements like humulene, beta-caryophyllene and linalool are powerful anti-inflammatory agents that work well in conjunction with cannabinoids. When a CBD product includes terpenes, the effects are more robust, onset faster, and last longer. As more research is being conducted around terpenes, it has become clear that to create CBD products without a profile of terpenes is to greatly limit their efficacy since terpenes are beneficial in their own right.
- Full Profile vs. Full Spectrum
When a product claims to be full spectrum they are referring to the full spectrum of cannabinoids. This means that the extract isn’t distilled to remove and concentrate specific cannabinoids. The cannabinoid ratio that is found in the original plant will be as similar as possible to the ratio in the product or extract. Extracting full spectrum products usually results in a loss of the more volatile terpenes. Another limitation of full spectrum products is the THC content in them. Full spectrum products contain THC and are psychoactive.
Full Profile products containing the entire profile of terpenes are hard to find. The reason is that most extraction techniques result in the loss of terpenes. In this case they require a reintroduction. Steam distilled cannabis is the most effective way of adding ful profile cannabis terpenes to a product. The heat from the steam causes the terpenes to vaporize, they are then collected using a condenser tube.
- What is CBDa?
CBDa is one of the three main compounds derived from Cannabigerolic Acid or CBGA which is the naturally occurring “mother of all cannabinoids”. Through an internal, enzyme-control reaction, CBGA is converted to THCA, CBDA and CBCA. In essence, CBDa is the precursor to CBD as the latter is derived from CBDa through a process known as carboxylation. More bioavailable.
- What is CBN?
CBN is a non-intoxicating compound that is best known as the cannabinoid created when THC ages. For that reason, it’s usually present in high amounts in older cannabis. It is considered to be antibacterial, nueroprotectant and an appetite stimulant.
General Wellness Questions about CBD
- Who can take CBD products?
Provided you procure your CBD products from a reliable vendor, they are generally safe to use for people of all ages and backgrounds. While you might have to be 18 or older to buy CBD products, they are often administered to minors for the treatment and management of certain health and wellness issues such as anxiety and autism. We do however recommend that make sure CBD does not counteract with any medications that you are already taking. This is why we recommend that you consult your doctor if you are already on some kind of medication before taking any CBD products.
- Does CBD make you sleepy?
Depending upon how the CBD is used in conjunction with other ingredients, CBD can actually make you sleepy or help you focus more. CBD shows hormetic properties, which means that at low doses an opposite effect is seen as compared to high doses.Dosage as well as formulation synergy have drastic effects on how CBD works. Hence, you should always look to purchase CBD products that meet your specific requirements. For more information, click here.
- Can I overdose on CBD?
In order for CBD to be toxic to your system, you would have to ingest almost 20,000 mg of CBD oil in a very short amount of time. This however, does not mean that you should consume CBD products in large quantities. Your best bet is to stick to the prescribed dosage clearly mentioned for each type of CBD product.
- Are there any negative side effects of CBD?
CBD is a remarkably well tolerated compound. However, in certain cases CBD consumption can cause some side effects such as dry mouth, diarrhea, drowsiness, reduced appetite or fatigue. In other cases CBD might interact with other medications, especially blood thinners. The most important factor to consider is the reliability and purity of the particular CBD product you are using. The better the quality of the product and the more reliable the brand, the less likely you are to experience any negative side effects of CBD.
- Does CBD make you high?
CBD is a non-psychoactive compound. CBD in and of itself does not make you high. THC is the compound that makes you high however most CBD products contain little to no traces of CBD. For more information click here.
- How much CBD oil should I take?
If you’re just starting out, it’s best to start with a low dosage and gradually increase your intake as your body gets used to it. Most CBD products come with clear dosage instructions and for best results you should follow the prescribed dosage.
- Which CBD product is right for me?
It depends on your health and wellness needs. The market is flooded with a diverse range of CBD products that are especially designed to target specific health issues. From pain management to anxiety and inflammation to sleep aids, you’ll be able to find a CBD product that is a perfect fit for your health needs.
- Can you give CBD to your pets?
Yes! CBD products are a great way to improve the health and wellness of your pets. Many brands are now manufacturing CBD products exclusively for pets however certain standard products can help pets in the same way as they help humans.
Questions about Medicileaf’s CBD products and brand
- Do you have a CBD store?
Yes! We have a brick and mortar CBD store called the CBD Marketplace in Santa Rosa, CA. For more information and directions click here.
- Do you offer your products at wholesale?
Yes! Medicileaf offers a compelling wholesale program that allows you to take advantage of one of the fastest growing industries.Whether you’re an independent entrepreneur, a retail business or a healthcare professional – our CBD Wholesale Program enables you to buy our premium range of CBD products at wholesale rates and grow your CBD business. For more information and application click here.
- Does Medicileaf have an affiliate program?
Yes! Our CBD Affiliate Program enables you to get started in the CBD industry by offering Medicileaf’s line of premium CBD products to your friends, family and followers. Our affiliate program is designed to offer you the fastest, most cost-effective and risk-free opportunity to build a CBD business! To apply as an affiliate and get more details click here.
- Can I private label your CBD products?
Yes. We offer a White Label Program that enables you to sell our proprietary blends with your original brand. Our CBD White label program allows you to build your own CBD brand by offering our premium products under your own private label. For more information click here.
Legal Questions and Concerns about CBD
- Are CBD products legal in the USA?
CBD products are legal in all 50 states across the United States.
- Do I need a doctor’s or a marijuana card prescription to buy CBD products?
No. You can easily purchase CBD products over the counter or online.
- Does CBD show up in drug tests?
CBD does not show up in drug tests because drug tests are not looking for traces of CBD. In some cases, CBD products may contain THC or traces of THC in which case that will show up in a drug test.
- Can I fly with CBD products?
It is perfectly legal to fly with CBD products across the United States. However, if you wish to travel internationally then it is best to check the regulations around CBD for that specific country.
- CBD MCT Oil Tinctures: 300mg, 500mg, 1000mg, 1500mg.
Cannabidiol (CBD): a non-psychoactive cannabinoid that is derived as a metabolite of CBG.
Uses: Addiction treatment, epilepsy, fibromyalgia, PTSD, Crohn’s Disease, Insomnia, Anti-inflammation, antipsychotic, neuro-protectant, anxiolytic, cancer treatment.
Interactions: CBD is a potent Cytochrome (CYP3A4 & CYP2D6) inhibitor. As such it may increase the serum concentrations of macrolides, calcium channel blockers, benzodiazepines, cyclosporine, sildenafil, antihistamines, haloperidol, antiretrovirals, and some statins. Also, CBD may increase serum concentrations of many antidepressants including SSRIs, tricyclic antidepressants, antipsychotics, beta blockers and opioids.
Side Effects: CBD is non-psycho active in the human body. Some rare cases report sleepiness upon over consumption.
MCT Oil: stands for “medium chain triglycerides,” and is one of two carriers used in Presta tinctures. This oil is converted directly into ketones in the liver. Our MCT is organic and purely coconut derived.
Uses: Appetite control, anti-convulsive, lowers blood sugar, increases nutrient absorption.
Interactions: Too much MCT oil can result in gastric distress. Do not consume more than 3 ounces of MCT without consulting your doctor.
Cannabis Derived Terpenes: are a specific ratio of compounds that provide support and amplification of the other compounds in this mixture. Each specific terpene found below has a specific function, together they attack disease and amplify wellness from many physiological angles.
Uses: Anxiolytic, sedative properties, anti-epileptic, increased bioavailability, anticancer, anti-inflammatory.
Interactions: As with all health compounds, caution is recommended when consuming other medications on top of these compounds. Terpenes increase bioavailability, while it is not clinically proven, one should assume that all other medications taken may be absorbed to a higher degree.
- Night Cap Sleep Promoter:
Cannabidiol (CBD): stands at the forefront of cannabinoid therapy. CBD is a non-psychoactive cannabinoid that is derived as a metabolite of CBG.
Uses: Addiction treatment, epilepsy, fibromyalgia, PTSD, Crohn’s Disease, Insomnia, Anti-inflammation, anti-psychotic, neuro-protectant, anxiolytic, cancer treatment.
Interactions: CBD has been shown to be a potent Cytochrome (CYP3A4 & CYP2D6) inhibitor. As such it may increase the serum concentrations of macrolides, calcium channel blockers, benzodiazepines, cyclosporine, sildenafil, antihistamines, haloperidol, anti-retrovirals, and some statins. Also, CBD may increase serum concentrations of many antidepressants including SSRIs, tricyclic antidepressants, antipsychotics, beta blockers and opioids.
Side Effects: CBD has been shown to be very amenable to the human body, however some rare cases report sleepiness as a result if too much is taken.
Cannabinol (CBN): a metabolite of THC, the only compound in cannabis that works to promote sleep. CBN is a degraded version of THC, it is non-psychoactive but does cause drowsiness.
Uses: Sleep promotion, pain reduction, anxiolytic.
Interactions: Caution and a doctor’s recommendation should be used if taking CBN with other medications.
Side Effects: CBN may cause excessive drowsiness and potential in the human system, drowsiness may be observed.
Oleamide: is a compound produced in the mammalian brain. It interacts with the body’s cannabinoid receptors and is thus deemed an endocannabinoid. Oleamide is produced in high volumes in the brain when it is sleep deprived.
Uses: Anxiolytic, sleep promoter, elevates mood, increases appetite.
Interactions: Oleamide interacts with the endocannabinoid system. Oleamide has been shown to be active on many neurotransmitter systems and as such should be taken with caution if other pharmaceutical medications are being administered.
Side Effects: Oleamide does not show any significant side effects. Oleamide is found naturally in the human system as an “endocannabinoid.”
CO2 Hops Extract: s derived from Humulus lupulus which is the hops commonly known for making beer. Humulus lupulus is in the same family as cannabis.
Uses: Promotes relaxation, reduces anxiety, improves sleep.
Interactions: Hops has been shown to work very well in conjunction with Valerian extracts. Research has yet to separate the sleep promoting aspects of hops by itself.
Side Effects: When taken in moderate doses, hops extracts do not cause side effects.
95% Honokiol and Magnolol Extract: a plant based extract from the magnolia plant. These compounds work with the GABA neurotransmitter system to reduce stress, turn down neural activity and induce sleep.
Sleep Promoting Terpene Blend: blend of terpenes from cannabis and other plants that provides support and amplification of the other compounds in this mixture. Each specific terpene found below has a specific function, together they enhance and supplement the sleeping process.
Uses: Anxiolytic, sedative properties, anti-epileptic, increased bioavailability, anticancer, anti-inflammatory.
Interactions: As with all health compounds, use caution when consuming other medications in conjunction with these compounds. Terpenes increase bio-availability, while it is not clinically proven, one should assume that all other medications taken may be absorbed to a higher degree.
Side Effects: The amount of terpenes in these products will not produce side effects. If taken in excess terpenes can cause gastrointestinal problems.
Please feel free to reach out to us at firstname.lastname@example.org for any further queries or to speak to an expert about CBD products.